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MS Article


What is Progressive Relapsing

 Multiple Sclerosis?



Progressive Relapsing Multiple Sclerosis (PRMS) is a rare form of MS that is characterized by a steady increase in disability, along with exacerbations and remissions, that are not as drastic as those that are seen with the majority of cases of Relapsing and Remitting Multiple Sclerosis.  Because it is so rare, not as much is known or understood about Progressive Relapsing Multiple Sclerosis.

Just after a relapse, or exacerbation, in Progressive Relapsing MS (PRMS) there is an improvement in symptoms, but the plateaus between exacerbations are not as lengthy as is reported to occur with most cases of Primary Progressive MS.  However, there is a general worsening of the symptoms during the time between relapses.  Progressive Relapsing Multiple Sclerosis does not go though extended plateaus like the majority of the cases of Primary Progressive Multiple Sclerosis do.

Progressive Relapsing Multiple Sclerosis attacks and damages the nerves throughout the Central Nervous System, which include the Brain, the Spinal cord and the nerves throughout the body, even when there are times where symptoms do not occur to signal that the nerve damage is continuing to progress and worsen the resulting disability.

Relapses or flare ups occur periodically followed by partial or full recovery, but in spite of it appearing that the recovery was total, the nerve damage continues to progress and symptoms continuing to become increasingly disabling.

Progressive Relapsing Multiple Sclerosis affects around 5% of those that have been diagnosed with MS. Some neurologists believe that Progressive Relapsing MS is a more advanced form of the Primary Progressive Multiple Sclerosis, although this has not been confirmed.

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