Have you heard about the
news that MS patients are talking about and how this discovery is stirring
hope for the estimated 2.3 million people, who have been diagnosed with
Multiple Sclerosis around the world?
This amazing discovery has the potential of helping thousands of people
around the world, who have been diagnosed with Multiple Sclerosis. This
breakthrough could possibly even change the way that the medical
community around the world views Multiple Sclerosis on both how it is
classified and how it is treated.
On November 21st, an amazing breakthrough for the treatment of Multiple
Sclerosis (MS) was aired on the news across Canada, that described
about a new discovery by Dr. Paolo Zamboni, an Italian vascular
surgeon. According to Dr. Zamboni, he found that there is a structural
defect that exists in the blood vessels of the MS patients that he
treated, which could be causing symptoms of Multiple Sclerosis. This
interesting discovery has peaked the curiosity of the medical community
around the world.
Dr. Paolo Zamboni, a vascular
Ferrara, Italy discovered that most of the MS patients that he was
had restricted or reduced blood flow to and from the brain from venous
insufficiency to the blood vessels of the neck and the upper chest
Dr. Zamboni was initially
prompted to do the
research, which lead up to his findings, by the fact that his wife,
diagnosed with Multiple Sclerosis ten years earlier. Over the
time after his wife was diagnosed with MS, Dr. Zamboni saw his
wife gradually losing
more of her abilities to function on her own and this prompted him to
further evaluations of MS patients, located in Ferrara,
Italy to see
if any thing could possibly help his wife.
Dr. Zamboni observed initially
that the MS patients
that he was evaluating had much higher levels of iron in the
compared to people without the diagnosis of Multiple Sclerosis.
began by posing questions
about the phenomenon of iron deposits in the brains of patients with
MS. He wondered if it was possible that the iron came from
improperly collecting in the brain.
Examining MS patients
with Doppler ultrasound, he found 90% of the patients had narrowing or
of the veins that allowed blood flow to and from he brain.
MS were also tested and they did not have these blockages of the veins
neck and upper chest regions.
testing, Dr. Zamboni
determined that the majority of the MS patients had either partial
some other type of restriction to the blood flow to the
in the neck or to the veins in the neck or upper chest
regions, which reduced blood
flow to and from the brain.
thinks that due to the
dysfunction of drainage of the veins, the blood reverses back into the
where extra iron is deposited. He called this vein disorder
Chronic Cerebrospinal Venous Insufficiency or CCSVI.
mend these blockages, Dr.
Zamboni developed a surgical procedure to improve blood flow into the
opening up veins in the neck and the upper chest. The
procedure involved inserting a catheter into each of the affected veins
and a small balloon was inflated to open up the pathway of
blood flow to the brain to help to increase the blood flow to the brain.
According to the
he has performed his surgery, called “la liberation” in Italian, on 120
Because the surgery freed the blood
flow, the team dubbed
the procedure “The
Once Dr. Zamboni
made his initial discovery, he located a neurologist, who
worked with him to conduct a 2 year study on 120 MS patients in
Ferrara, Italy to investigate his findings further. The MS patients
that were found to have blockages or restricted blood flow to the neck
and the upper chest underwent The Liberation surgical procedure.
Out of the 120 patients in the
study, 73% of them
showed improvements after the surgery, with some remarkable results
within the first 6 months after the surgery was performed.
Dr. Zamboni thinks that due to
the dysfunction of drainage of the veins, the blood reverses back into
the brain, where extra iron is deposited. Dr. Zamboni called
the vein disorder Chronic Cerebrospinal Venous Insufficiency or CCSVI.
This most recent MS news hopes can help,
that shows potential,
but will need to be investigated further before more wide spread
benefits can be realized through performing more clinic trials and
clinical trials have
begun based on his findings. Dr. Robert Zividinov, of the University of Buffalo, hopes
to enroll MS
patients, from the United States
to undergo ultrasound and MRI neck scans to detect blocked veins.
A study of 65
patients afflicted with
MS will be published in the “Journal
of Vascular Surgery”.
These patients underwent the Liberation
Some patients that were interviewed stated that they had no MS attacks
The MS Societies
and the U.S.
are cautious in their support of Dr. Zamboni’s work thus far.
this new discovery seems to be generating a lot of interest among MS
patients. And some surgeons in the U.S.
are now offering Dr. Zamboni’s surgery. Multiple Sclerosis
2.5 million people worldwide.
Zamboni is a former vascular
surgeon and professor at the University
prompted to do his research on MS, since his wife, Elena, had been
with Multiple Sclerosis ten years before he started his research.
This is what prompted Dr. Zamboni to decide to help his wife
more about MS.
But all of this
began with a husband's
labor of love with trying to help find a way to reduce his wife’s
with MS and to help her to find something to help her to
recover to some
degree from the devastating effects of Multiple Sclerosis on her
Elena, Dr. Zamboni’s wife, was one of his first patients to receive the
surgery. After many years of MS attacks, she now
has no signs of a
To see more of
the series of videos about
this amazing discovery and to find more resources and contacts --
these can be found on CTV’s