Have you heard about the
recent MS breakthrough which MS patients are talking about and how this discovery is stirring
hope for the estimated 2.3 million people, who have been diagnosed with
Multiple Sclerosis around the world?
This amazing discovery has the potential of helping thousands of people
around the world, who have been diagnosed with Multiple Sclerosis. This
breakthrough could possibly even change the way that the medical
community around the world views Multiple Sclerosis on both how it is
classified and how it is treated.
On November 21st, an amazing breakthrough for the treatment of Multiple
Sclerosis (MS) was aired on the news across Canada, that described
about a new discovery by Dr. Paolo Zamboni, an Italian vascular
Dr. Paolo Zamboni, a vascular surgeon in
Ferrara, Italy discovered that most of the MS patients that he was working with
had restricted or reduced blood flow to and/or from the brain from venous
insufficiency to the blood vessels of the neck and the upper chest regions. This
interesting discovery has peaked the curiosity of the medical community
around the world.
Dr. Zamboni was initially prompted to do the
research, which lead up to his findings, by the fact that his wife, Elena, was
diagnosed with Multiple Sclerosis ten years earlier. Over the period of
time after his wife was diagnosed with MS, Dr. Zamboni saw his wife gradually losing
more of her abilities to function on her own and this prompted him to do
further evaluations of MS patients, located in Ferrara, Italy to see
if any thing could possibly help his wife.
Dr. Zamboni observed initially that the MS patients
that he was evaluating had much higher levels of iron in the brain,
compared to people without the diagnosis of Multiple Sclerosis.
Zamboni began by posing questions
about the phenomenon of iron deposits in the brains of patients with
Multiple Sclerosis. He wondered if it was possible that the iron came from blood
improperly collecting in the brain.
with Doppler ultrasound, he found 90% of the patients had narrowing or
of the veins that allowed blood flow to and from he brain. People
Multiple Sclerosis were also tested and they did not have these blockages of the veins
neck and upper chest regions.
Dr. Zamboni thinks that due to the
dysfunction of drainage of the veins, the blood reverses back into the brain,
where extra iron is deposited. He called this vein disorder
Chronic Cerebrospinal Venous Insufficiency or CCSVI.
To mend these
Zamboni developed a surgical procedure to improve blood flow into the
opening up veins in the neck and the upper chest. The procedure
involved inserting a catheter into each of the affected veins and inflating a
small balloon to open up the pathway of blood flow
to the brain to help to increase the blood flow to the brain.
According to the CTV reports,
he has performed his surgery, called “la liberation” in Italian, on 120 MS patients.
Because the surgery freed the blood flow, the team dubbed
the procedure “The Liberation Treatment.”
Dr. Zamboni made his initial discovery, he located a neurologist,
who worked with him to conduct a 2 year study on 120 MS patients in
Ferrara, Italy to investigate his findings further. The MS patients
that were found to have blockages or restricted blood flow to the neck
and the upper chest underwent The Liberation surgical procedure.
Out of the 120 patients in the study, 73% of them
showed improvements after the surgery was performed, with some remarkable results being seen
within the first 6 months after the surgery was performed.
This most recent MS breakthrough
shows potential, but will need to be investigated further before more
wide spread benefits can be realized through performing more clinic
trials and studies.
Investigative clinical trials have
begun based on Dr. Zamboni's findings. Dr. Robert Zividinov, of the University of Buffalo, hopes to enroll MS
patients, from the United States and Canada,
to undergo ultrasound and MRI neck scans to detect blocked veins.
A study of 65 patients afflicted with
MS will be published in the “Journal of Vascular Surgery”.
These patients underwent the Liberation Treatment.
Some patients that were interviewed stated that they had no MS attacks since
The MS Societies of Canada and the U.S.
are cautious in their support of Dr. Zamboni’s work thus far. But
this new discovery seems to be generating a lot of interest among MS
patients. And some surgeons in the U.S.
are now offering Dr. Zamboni’s surgery. Multiple Sclerosis (MS) afflicts
2.5 million people worldwide.
Dr. Paola Zamboni is a former vascular
surgeon and professor at the University
in Italy, who was
prompted to do his research on MS, since his wife, Elena, had been diagnosed
with Multiple Sclerosis ten years before he started his research.
This is what prompted Dr. Zamboni to decide to help his wife by learning
more about MS.
But all of this began with a husband's
labor of love with trying to help find a way to reduce his wife’s suffering
with MS and to help her to find something to help her to recover to some
degree from the devastating effects of Multiple Sclerosis on her body.
Elena, Dr. Zamboni’s wife, was one of his first patients to receive the
surgery. After many years of MS attacks, she now has no signs of a
To see more of the series of videos about
this amazing discovery and to find more resources, contacts and additional links about the MS breakthrough --
these can be found on CTV’s Website.